Although initiation of bacterial infection through contaminated blood
products via transfusion is a relatively infrequent occurrence, bacterial
sepsis as a result of transfusion of contaminated blood products has been
reported. Examples of two implicated pathogens include Pseudomonas fluorescens
and Yersina enterocolitica. Blood donors are interviewed at the
time of donation regarding their overall feelings of general health, but
unfortunately this cursory interview does not rule out contamination of
blood in individuals with asymptomatic disease. Contamination of the donated
blood with flora of the skin, or contamination during the processing of
the blood unit may also occur.
1. Would you assume that the incidence of bacterial infection due to contaminated blood products is over or under reported. Why?
2. Suggest some ways that blood products could be screened to prevent
transfusion associated infections. Are any of your suggestions practical?
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